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Genomics

The SEA-AD Integrative Analysis Center Study (SEA-AD IAC)

The Seattle Alzheimer's Disease Brain Cell Atlas Integrative Analysis Center (SEA-AD IAC) reprocesses datasets from SEA-AD and other large-scale Alzheimer's disease and related dementia studies to support harmonized cross-study analyses. The study provides uniformly processed single-cell genomics and multiomic data, harmonized metadata, and representations of disease pathology mapped to highly annotated BRAIN Initiative Cell Atlas Network (BICAN) and SEA-AD cell classifications. These resources support investigation of cell-type-specific molecular changes across Alzheimer's disease cohorts and stages of disease progression.

Listed for discovery. Access is provided by the original publisher under its terms.

Data coverage

The Seattle Alzheimer's Disease Brain Cell Atlas Integrative Analysis Center (SEA-AD IAC) reprocesses datasets from SEA-AD and other large-scale Alzheimer's disease and related dementia studies to support harmonized cross-study analyses. The study provides uniformly processed single-cell genomics and multiomic data, harmonized metadata, and representations of disease pathology mapped to highly annotated BRAIN Initiative Cell Atlas Network (BICAN) and SEA-AD cell classifications. These resources support investigation of cell-type-specific molecular changes across Alzheimer's disease cohorts and stages of disease progression.

Access & permitted use

Review the publisher’s documentation for availability, eligibility and permitted uses, including commercial analysis, model training and redistribution.

https://adknowledgeportal.synapse.org/Explore/Studies/DetailsPage/StudyDetails?Study=syn64410371Acknowledgement

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